In my day, we didn't have self-esteem, we had self-respect, and no more of it than we had earned.
The more comprehensible the universe becomes the more pointless it seems.
The effort to understand the universe is one of the very few things that lifts human life a little above the level of farce, and gives it some of the grace of tragedy.
Most scientists I know don't care enough about religion even to call themselves atheists.
The more we refine our understanding of God to make the concept plausible, the more it seems pointless.
This is often the way it is in physics - our mistake is not that we take our theories too seriously, but that we do not take them seriously enough. It is always hard to realize that these numbers and equations we play with at our desks have something to do with the real world. Even worse, there often seems to be a general agreement that certain phenomena are just not fit subjects for respectable theoretical and experimental effort.
It is positively spooky how the physicist finds the mathematician has been there before him or her.
Perhaps we had at last reached that stage of intimacy that destroys intimacy.
Those are not the tears of repentance!. . . Self-loathing is not sorrow. Yet it is good, for it marks a step in the way home, and in the father's arms the prodigal forgets the self he abominates.
Your job today is to pass gas. You do that and we can start feeding you liquids. No fart, no food.
I think all the beer I drank in college created an iron bladder.