Writers block: when I get it, it's because my subconscious spotted that I'd make a huge structural mistake in constructing a novel before my conscious mind became aware of it, and threw on the brakes. So I've learned not to sweat it: take two days off, then back up a chapter, read through, and try to work out why I'm suddenly uneasy about continuing.
Most people, if they're doing really well in their career, often don't have the right intimacy with their partner, or they're doing great in their home life, but their finances are a mess.