As Christ was born of the Virgin's womb, so must He be spiritually formed in our hearts. As He died for sin, so must we die to sin. And as He rose again from the dead, so must we also rise to a divine life.
On any Tuesday morning, if asked, a good working scientist will tell you with some self-satisfaction that the affairs of his field are nicely in order, that things are finally looking clear and making sense, and all is well. But come back again on another Tuesday, and the roof may have just fallen in on his life's work.