If you're living life from a place of fear, you're not free to take risks or pursue your dreams. If your energy is expended in avoiding failure or rejection, then that energy is used to stay safe, instead of being available to create the life you envision.
I'd always enjoyed the comics more, and felt that as long as I was unemployed it would be a good chance to pursue that and see what response I could get from asyndicate, as I didn't have anything to lose at that point. So I drew up a comic strip - this was in 1980 - and sent it off and got rejected. I continued that for five years with different comic strip examples 'til finally Calvin and Hobbes came together. But it's been a long road.