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You'd better discover a more important motive than publication for your work or else you'll go crazy. My sense is that you'll be writers only if you are convinced that to write is something for which there is no substitute in your life. You must therefore be ambitious for your work rather than for its promotion. The good news here is that if you assign secondary importance to publishing and primary to writing itself, you will write better, and will thus increase your odds of getting publishing.

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Randy Schekman

I was driven completely by a desire to understand how cells worked.

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